Prognostic significance of stromal versican expression in human endometrial cancer.

5-Year Survival in Gastric Adenocarcinoma with Epithelial and Stromal Versican Expression

Background & Objective: Gastric cancer is the second most frequent cause of cancer death worldwide, despite differences in incidence around the world. The majority of gastric cancer cases concern gastric adenocarcinoma, which has a fairly high 5-year survival rate when coupled with early-stage diagnosis. Versican, a member of the aggregating chondroitin sulfate proteoglycans fa...

Expression and Clinical Significance of Activating Transcription Factor 3 in Human Breast Cancer

  Objective(s): Breast cancer is the most common type of cancer among women worldwide. This study investigated the expression and clinical significance of activating transcription factor 3 (ATF3) in human breast cancer and its relationship with the clinical outcome of breast cancer.   Materials and Methods : ATF3 expressions were detected in 114 primary breast cancer tissues and ...

Adiponectin Effect on The Viability of Human Endometrial Stromal Cells and mRNA Expression of Adiponectin Receptors

P-96: Survey of In Vitro Effect of Noscapine on Nitric Oxide Secretion of Human Endometrial Stromal Cell

Background: Noscapine is cough suppressant drug with cell inhibitory effect. It is introduced for anti-cancer treatment. The aim of present study was to determine in vitro noscapine effect on nitric oxide (NO) secretion by human endometrial stromal cells. Materials and Methods: Human endometrial biopsies (n=8) were obtained in sterile condition and were chopped mechanically and digested by enzy...

Angiogenesis Following Three-Dimensional Culture of Isolated Human Endometrial Stromal Cells

Background Endometriosis is the presence of endometrial tissue outside of the uterine cavity and is the most common gynecologic disorder in women of reproductive age. We have preliminary evidence that in the presence of a 3-dimensional (3-D) fibrin matrix, human endometrial glands, stroma, and neovascularization can develop in vitro, mimicking the earliest stages of endometriosis. The aim of th...